Onglyza (Saxagliptin)

Generic Onglyza (Saxagliptin)

Saxagliptin tablet is a medicine used to treat type 2 diabetes. It is used to control blood sugar levels in conjunction with a balanced diet and frequent exercise. By doing this, major diabetes complications like kidney damage and blindness are less likely to occur.

Onglyza Information :

Uses :

Saxagliptin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Keeping blood sugar levels under control can help avoid kidney damage, blindness, nerve damage, limb loss, and issues with sexual function. Keeping your diabetes under control may also reduce your chance of having a heart attack or stroke. Saxagliptin functions by raising the concentrations of incretins, which are organic compounds. Particularly after a meal, incretins increase the release of insulin, which aids in blood sugar regulation. They also lessen your liver’s production of sugar.

To maximize the benefits, take it consistently at the same time every day and don’t stop taking it unless directed by your physician. It regulates your blood sugar levels and aids in averting more severe issues down the road. It is imperative that you adhere to the prescribed diet and exercise regimen while using this medication. Diabetes management is greatly influenced by your lifestyle.

Precautions & Warnings :

When combined with other anti-diabetic medications or insulin therapy, Saxagliptin may increase the risk of hypoglycemia, or low blood sugar. In this situation, your physician might change the Saxagliptin dosage. Extended use of Saxagliptin may result in serious kidney problems and acute pancreatitis, or swollen pancreas. Some patients taking Saxagliptin may experience severe allergic reactions, such as anaphylaxis, angioedema (swelling beneath the skin), and exfoliative skin conditions such as Stevens-Johnson syndrome.

It is not recommended to give Saxagliptin to children under the age of 18 due to the lack of evidence regarding its efficacy and safety. Patients who take Saxagliptin along with digoxin (a heart medication) should be closely watched because serious drug interactions have been reported.

Side Effects :

The following is a brief summary of some of the mild side effects that oral Saxagliptin tablets may have. Consult your physician or pharmacist, or review the prescribing information for Saxagliptin oral tablet, to find out about additional mild side effects.

Saxagliptin oral tablet mild side effects that have been documented include

• Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
• Upper respiratory tract infection
• Urinary tract infection
• Headache
• Peripheral edema

Many medications have mild side effects that usually go away in a few days or weeks. Consult your physician or pharmacist, though, if they start to cause you problems.

Interactions :

Antidepressants (bupropion), glaucoma medications, antibiotics (ciprofloxacin, cephalexin), anti-acidity medications (cimetidine), heart condition medications (digoxin), anti-HIV medications (dolutegravir), ethanol, saliva-reducing medications (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic medications (topiramate, lamotrigine), and heart-related chest medication (ranolazine) are among the medications that interact with saxagliptin. Other medications such as anti-oxidants (alpha-lipoic acid), growth hormones (pegvisomant), anti-TB drugs (prothionamide), aspirin, sex hormones (androgens), and other antidiabetic medications can also cause an elevated low blood sugar level.

Those with a history of pancreatitis or pancreatic disease as well as renal impairment should use saxagliptin with caution.

Overdose :

If someone has overdosed and is experiencing severe symptoms, such as unconsciousness or difficulty breathing, call 911. If not, immediately contact a poison control center.

Missed Dose : 

Try to take it at the same day every day. Do not double the dose if missed.

Storage :

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.